127099-85-8Relevant articles and documents
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Arndt
, p. 2239 (1921)
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Schmidt,E.
, p. 351 (1917)
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A New Method for Converting Thiourea and Monosubstituted Thioureas into Cyanamides: Desulphurisation by Superoxide Ion
Crank, George,Makin, Mahommad I. H.
, p. 53 - 54 (1984)
Superoxide ion, in aprotic media, converts thiourea and monosubstituted thioureas into cyanamides.
Nitrosation of Cyanamide: Preparation and Properties of the Elusive E- and Z-N'-Cyanodiazohydroxides
Guethner, Thomas,Huber, Evi,Sans, Juergen,Thalhammer, Franz
supporting information, (2020/04/29)
Nitrosation of cyanamide leads to unstable E/Z-cyanodiazohydroxides that easily deprotonate to E/Z-cyanodiazotates. Pursuing observations of E. Drechsel 145 years ago, the structure and reactivity of those products was determined, mainly in aqueous solution. Depending on the pH, three different thermal decomposition pathways give either N2O + HCN or N2 + HNCO. They were evaluated experimentally and by quantum mechanical calculations.
Formation of pyrimidin-2-ylcyanamide and 2-aminopyrimidine in the reaction of aniline derivatives with cyanamide and dimethylamino-1-pyridyl-2-propenone
Koroleva,Ignatovich, Zh.V.,Ignatovich,Gusak
scheme or table, p. 1222 - 1226 (2011/12/01)
Substituted o- and p-nitroanilines and m-benzylaminoanilines in the reaction with cyanamide failed to yield the corresponding arylguanidines, and in the presence of 3-dimethylamino-1-(3-pyridyl)-2-propen-1-one formed 4-pyridyl-substituted pyrimidin-2-ylcyanamides and 2-amino-pyrimidines.
2-substituted-4-nitrogen heterocycles as modulators of chemokine receptor activity
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, (2008/06/13)
The present application describes modulators of CCR3 of formula (I): or pharmaceutically acceptable salt forms thereof, useful for the prevention of asthma and other allergic diseases.