127181-68-4

Basic information

• Product Name: 6-O-α-D-glucopyranosyl-β-cyclodextrin
• CAS NO: 127181-68-4
• Molecular Weight: 1297.14
• Mol File: 127181-68-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 6-O-α-D-glucopyranosyl-β-cyclodextrin(CAS DataBase Reference)
• NIST Chemistry Reference: 6-O-α-D-glucopyranosyl-β-cyclodextrin(127181-68-4)
• EPA Substance Registry System: 6-O-α-D-glucopyranosyl-β-cyclodextrin(127181-68-4)

Safety Data

• Hazardous Substances Data: 127181-68-4(Hazardous Substances Data)

Upstream product

• 104723-62-8 6-O-α-D-maltotriosyl-β-cyclodextrin 
• 2280-44-6 D-Glucose 
• 7585-39-9 β‐cyclodextrin 
• 112269-46-2 6-O-α-(6³-O-α-maltotriosyl)maltotriosyl-cG7 
• 112269-47-3 6-O-α-(6²-O-α-maltotriosyl)maltotriosyl-cG7 
• 116525-08-7 <2,3-di-O-acetyl-6-O-(α-D-glucopyranosyl)>hexakis(2,3,6-tri-O-acetyl)cyclomaltoheptaose 
• 104723-60-6 maltosyl(α1->6)β-cyclodextrin 

Relevant articles and documents

ISOLATION AND CHARACTERIZATION OF BRANCHED CYCLODEXTRINS

Three branched cyclodextrins (CDs) were isolated by high-performance liquid chromatography (l.c.) from the mother liquors of a large-scale preparation of the unbranched CDs with Bacillus ohbensis cyclomaltodextrin glucanotransferase.Evidence from chromatographic behavior on three l.c. coloumns of different separation modes, fragmentation analysis, 13C-n.m.r. spectroscopy, methylation analysis, and fast-atom bombardment-mass spectroscopy (f.a.b.-m.s.) indicated that these compounds were 6-O-α-D-glucopyranosylcyclomaltohexaose (1), 6-O-α-D-glucopyranosylcyclomaltoheptaose (2), and 6,6'''-di-O-α-D-glucopyranosylcyclomaltoheptaose (3).

ENZYMIC SYNTHESES OF DOUBLY BRANCHED CYCLOMALTOHEPTAOSES THROUGH THE REVERSE ACTION OF Pseudomonas ISOAMYLASE

Two and three new cyclomaltoheptaose (β-cyclodextrin, cG7) derivatives, respectively, were identified among the products obtained by the action of Pseudomonas isoamylase on maltose and maltotriose, and cG7.They were 6A,6D-di-O-α-maltosyl-cG7 and 6-O-α-(62-O-α-maltosyl)maltosyl-cG7, and 6A,6D-di-O-α-maltotriosyl-cG7, 6-O-α-(63-O-α-maltotriosyl)maltotriosyl-cG7, and 6-O-α-(62-O-α-maltotriosyl)maltotriosyl-cG7.In addition, 61- and 62-O-α-maltosylmaltose were identified as mutual condensation products of maltose.Maltose was the smallest substrate to act as both an acceptor and a donor for the action of Pseudomonas isoamylase.

Synthesis of branched cyclomalto-oligosaccharides using Pseudomonas isoamylase.

Branched cyclomalto-oligosaccharides (cyclodextrins) were synthesised from cyclomalto-oligosaccharides and maltose or maltotriose through the reverse action of Pseudomonas isoamylase. The reaction rate was greater with maltotriose than with maltose, and with increasing size of the cyclomalto-oligosaccharide (cG6 less than cG7 less than cG8). Maltotriose is effective as both a side-chain donor and acceptor, and three isomers of 6-O-alpha-maltotriosylmaltotriose (branched G6) were formed through mutual condensation, but maltose was effective only as a side-chain donor. Each branched cyclomalto-oligosaccharide and G6 was purified by liquid chromatography, and their structures were determined by chemical, enzymic, and 13C-n.m.r. spectroscopic analyses.