127220-93-3Relevant articles and documents
Palladium-catalyzed monoarylation of arylhydrazines with aryl tosylates
Huang, Yange,Choy, Pui Ying,Wang, Junya,Tse, Man-Kin,Raymond Wai-Yin Sun,Albert Sun-Chi Chan,Kwong, Fuk Yee
, p. 14664 - 14673 (2020)
A palladium-catalyzed C-N bond coupling reaction between arylhydrazines and aryl tosylates for facile synthesis of unsymmetrical N,N-diarylhydrazines has been developed. Employing the catalyst system of Pd(TFA)2 associated with newly developed phosphine ligand L1, the monoarylation of arylhydrazine proceeds smoothly to afford desired products in good-to-excellent yields (up to 95%) with good functional group compatibility. This method provides an alternative synthetic pathway for accessing structurally diversified N,N-diarylhydrazines from simple and easily accessible coupling components.