127253-05-8 Usage
Description
Clarithromycin 9-oxime is a derivative of clarithromycin, which is a semi-synthetic macrolide antibiotic and a derivative of erythromycin. It is an impurity found in clarithromycin and is denoted as Clarithromycin (9Z)-Oxime (Clarithromycin EP Impurity L).
Uses
Used in Pharmaceutical Industry:
Clarithromycin 9-oxime is used as an impurity in the production of clarithromycin, a semi-synthetic macrolide antibiotic. It is important to monitor and control the levels of this impurity to ensure the safety, efficacy, and quality of clarithromycin-based medications.
Check Digit Verification of cas no
The CAS Registry Mumber 127253-05-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,2,5 and 3 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 127253-05:
(8*1)+(7*2)+(6*7)+(5*2)+(4*5)+(3*3)+(2*0)+(1*5)=108
108 % 10 = 8
So 127253-05-8 is a valid CAS Registry Number.
127253-05-8Relevant articles and documents
Synthesis and structure-activity relationships of novel 8a-aza-8a-homoerythromycin A ketolides
Pavlovi?, Dra?en,Mutak, Stjepan
supporting information; body text, p. 5868 - 5880 (2010/10/20)
A series of novel 6-O-substituted 8a-aza-8a-homoerythromycin A ketolides was synthesized and evaluated for in vitro antibacterial activity. Key strategic elements of the synthesis include the base-induced E-Z isomerization of 3-O-descladinosyl-6-O-allyler
