127351-06-8

Basic information

• Product Name: N-(4-bromophenyl)-4-methylbenzenecarbothioamide
• CAS NO: 127351-06-8
• Molecular Formula: C₁₄H₁₂BrNS
• Molecular Weight: 306.2208
• Mol File: 127351-06-8.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 384.9°C at 760 mmHg
• Flash Point: 186.6°C
• Density: 1.467g/cm³
• Vapor Pressure: 3.95E-06mmHg at 25°C
• Refractive Index: 1.699
• CAS DataBase Reference: N-(4-bromophenyl)-4-methylbenzenecarbothioamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-bromophenyl)-4-methylbenzenecarbothioamide(127351-06-8)
• EPA Substance Registry System: N-(4-bromophenyl)-4-methylbenzenecarbothioamide(127351-06-8)

Safety Data

• Hazardous Substances Data: 127351-06-8(Hazardous Substances Data)

Upstream product

• 158525-82-7 4-methyl-N-(4-bromophenyl)-benzamide 
• 2617-78-9 N-(4-bromophenyl)formamide 
• 104-87-0 4-methyl-benzaldehyde 
• 622-97-9 1-ethenyl-4-methylbenzene 
• 106-40-1 4-bromo-aniline 
• 874-60-2 4-methyl-benzoyl chloride 

Relevant articles and documents

Method for promoting elemental sulfur to synthesize thioamide by mixed alkali in water phase

The invention provides a method for promoting elemental sulfur to synthesize a thioamide compound by a mixed alkali in a water phase, and belongs to the field of organic synthesis. According to the method, an aldehyde compound and an amide compound are us

Thioamide derivative and preparation method thereof

The invention discloses a thioamide derivative. The structural formula of the thioamide derivative is represented by the formula (I) or the formula (II). The invention also provides a preparation method of the thioamide derivative. According to the preparation method, alkali metal salts are taken as the alkalis, amines are directly coupled with alkenes and sulfur, and by selecting the alkali, twodifferent thioamide derivatives represented by the formula (I) and the formula (II) can be prepared from same raw materials. The provided preparation method has the advantages that the raw materials are cheap and easily available, the synthesis method is simple, and the cost is largely reduced. The provided thioamide derivatives can be used in fields such as bioactive molecules, drug synthesis, and the like, and has a wide application range.

Synthesis, anticancer activity and docking of some substituted benzothiazoles as tyrosine kinase inhibitors

Protein tyrosine kinases occupy a central position in the control of cellular proliferation and its inactivation might lead to the discovery of a new generation anticancer compounds. Substituted benzothiazoles have been found to mimic the ATP-competitive