127502-57-2

Basic information

• Product Name: 1-Benzyloxy-6-(p-fluorophenyl)-2,4-diisopropylbenzene
• CAS NO: 127502-57-2
• Molecular Weight: 362.487
• Mol File: 127502-57-2.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Benzyloxy-6-(p-fluorophenyl)-2,4-diisopropylbenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzyloxy-6-(p-fluorophenyl)-2,4-diisopropylbenzene(127502-57-2)
• EPA Substance Registry System: 1-Benzyloxy-6-(p-fluorophenyl)-2,4-diisopropylbenzene(127502-57-2)

Safety Data

• Hazardous Substances Data: 127502-57-2(Hazardous Substances Data)

Upstream product

• 127502-55-0 2-Bromo-4,6-diisopropylphenol 
• 2215-21-6 3,5-diisopropylsalicylic acid 
• 2934-05-6 2,4-diisopropylphenol 
• 352-34-1 4-fluoro-1-iodobenzene 
• 127502-56-1 1-Benzyloxy-2-bromo-4,6-diisopropylbenzene 
• 460-00-4 1-Bromo-4-fluorobenzene 

Relevant articles and documents

Modified bile acid conjugates, and their use as pharmaceuticals

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Arylation of Phenols. Convenient, Regiospecific Methods for Mono- or Bis-p-fluorophenylations, Suitable for Large Scale Syntheses

Phenols have been arylated by a palladium(0)-catalyzed coupling reaction.Two methods were used: a Grignard reagent of a protected phenol component 2 was coupled with a haloarene, or an umpolung (reversed reactivity) where unprotected phenolic halides 6 were coupled with aryl Grignard reagents.Bis-arylation and regiospecific ortho-, meta- and para-arylations were achieved.Aryl-aryl-couplings were insensitive to steric hindrance in the Grignard component, but were inhibited by sulfur-containing substituents in the phenolic component.A thiocyanate substituted biaryl was used to synthesize arylated phenols with various sulfur functionalities.