1275609-46-5Relevant articles and documents
Arylation of [6,6]-spiroacetal enol ethers: Reactivity and rearrangement
Aumann, Kylee M.,Healy, Peter C.,Coster, Mark J.
, p. 1070 - 1073 (2011/03/22)
Attempts to selectively arylate [6,6]-spiroacetal enol ethers at the 2-position delivered unexpected results. Palladium-mediated arylation conditions afforded the double-Heck product, whereas reaction with benzenesulfinic acid resulted in a facile rearrangement into the corresponding 5-phenylsulfonyl-3,4, 5,6-tetrahydrochromans, providing access to 5-aryl-3,4,5,6-tetrahydrochroman and hexahydrochroman derivatives.