127563-53-5Relevant articles and documents
SYNTHESE DANS LA SERIE DES PHENANTHRIDINES I. RECHERCHES DES CONDITIONS EXPERIMENTALES OPTIMALES DANS LA PREPARATION D'ALKYL-6 PHENANTHRIDINES ET DE LEUR SEL
Lion, C.,Boukou-Poba, J. P.,Charvy, C.
, p. 557 - 566 (2007/10/02)
The synthesis of 6-alkylphenanthridines and their corresponding salts has been developed.The well known "biphenyl method" has been studied.Acylation of o-aminobiphenyl is achieved by an acid or the corresponding anhydride or acyl chloride.Cyclization of the intermediate o-acylamidobiphenyl has been studied in various conditions (solvents, temperature...).Quaternization has also been accomplished: new 6-alkylphenanthridinium salts have been prepared in good yields.