1276020-27-9

Basic information

• Product Name: C₁₉H₃₀O₅
• Synonyms: C₁₉H₃₀O₅
• CAS NO: 1276020-27-9
• Molecular Weight: 338.444
• Mol File: 1276020-27-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₉H₃₀O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₃₀O₅(1276020-27-9)
• EPA Substance Registry System: C₁₉H₃₀O₅(1276020-27-9)

Safety Data

• Hazardous Substances Data: 1276020-27-9(Hazardous Substances Data)

Upstream product

• 1276019-92-1 C₁₄H₂₀O₄ 
• 1276020-25-7 C₂₃H₃₈O₅ 
• 55362-80-6 9-bromononan-1-ol 
• 13321-73-8 2-bromo-1,5-dimethoxy-3-methylbenzene 
• 149051-24-1 ω-bromononanyl dimethyl-tert-butylsilyl ether 

Relevant articles and documents

Synthesis, modification, and evaluation of (R)-de-O-methyllasiodiplodin and analogs as nonsteroidal antagonists of mineralocorticoid receptor

Macrolide (R)-de-O-methyllasiodiplodin (1), discovered to be a potent nonsteroidal antagonist of the mineralocorticoid receptor (MR), was synthesized via an efficient method and evaluated for MR antagonistic activity together with its analogs. Among all the tested compounds, compounds 18a, 18b and 18c, exhibited more potent antagonistic activity against MR with IC50 values ranging from 0.58 to 1.11 μM. Generally, it was obviously demonstrated that acetylation at phenolic hydroxyl groups and the ring size in analogs of 1 were very important for MR antagonist activity.