1276024-98-6

Basic information

• Product Name: 1-(1H-benzo[d]imidazol-5-yl)-5-(4-(4-oxocyclohexyl)phenyl)imidazolidin-2-one
• Synonyms: 1-(1H-benzo[d]imidazol-5-yl)-5-(4-(4-oxocyclohexyl)phenyl)imidazolidin-2-one
• CAS NO: 1276024-98-6
• Molecular Weight: 374.442
• Mol File: 1276024-98-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(1H-benzo[d]imidazol-5-yl)-5-(4-(4-oxocyclohexyl)phenyl)imidazolidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1H-benzo[d]imidazol-5-yl)-5-(4-(4-oxocyclohexyl)phenyl)imidazolidin-2-one(1276024-98-6)
• EPA Substance Registry System: 1-(1H-benzo[d]imidazol-5-yl)-5-(4-(4-oxocyclohexyl)phenyl)imidazolidin-2-one(1276024-98-6)

Safety Data

• Hazardous Substances Data: 1276024-98-6(Hazardous Substances Data)

Upstream product

• 149507-27-7 4-(4-cyanophenyl)cyclohexanone-ethylene ketal 
• 1276024-99-7 C₁₅H₁₈O₃ 
• 1276025-00-3 C₂₃H₂₄N₄O₂ 
• 1276025-01-4 C₂₃H₂₈N₄O₂ 
• 1276025-02-5 C₂₄H₂₆N₄O₃ 
• 73204-07-6 4-(4-cyanophenyl)cyclohexanone 

Relevant articles and documents

NOVEL INHIBITORS

The invention relates to novel pyrrolidine derivatives of formula (I): wherein R1, R2 and R3 are as defined herein, as inhibitors of glutaminyl cyclase (QC, EC 2.3.2.5). QC catalyzes the intramolecular cyclization of N-terminal glutamine residues into pyroglutamic acid (5-oxo-prolyl, pGlu*) under liberation of ammonia and the intramolecular cyclization of N-terminal glutamate residues into pyroglutamic acid under liberation of water.