1276113-19-9 Usage
Chemical structure
A compound consisting of a trimethylsilylphenyl group attached to a nonafluorobutane-1-sulfonate group.
Usage
Commonly used as a reagent in organic synthesis, particularly in the fluorination of organic compounds.
Reactivity
Highly reactive and versatile, capable of selectively introducing fluorine atoms into various organic molecules.
Protecting group
The trimethylsilyl group can serve as a protecting group for alcohols and amines, making it a valuable tool in organic chemistry.
Stability
The nonafluorobutane-1-sulfonate group provides stability to the compound.
Solubility
The nonafluorobutane-1-sulfonate group enhances solubility in many organic solvents.
Utility
Highly useful in a wide range of chemical reactions due to its stability and solubility.
Check Digit Verification of cas no
The CAS Registry Mumber 1276113-19-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,7,6,1,1 and 3 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1276113-19:
(9*1)+(8*2)+(7*7)+(6*6)+(5*1)+(4*1)+(3*3)+(2*1)+(1*9)=139
139 % 10 = 9
So 1276113-19-9 is a valid CAS Registry Number.
1276113-19-9Relevant articles and documents
2-(Trimethylsilyl)phenyl Trimethylsilyl Ethers as Stable and Readily Accessible Benzyne Precursors
Ikawa, Takashi,Masuda, Shigeaki,Nakajima, Hiroki,Akai, Shuji
, p. 4242 - 4253 (2017/04/27)
Stable 2-(trimethylsilyl)phenyl trimethylsilyl ethers, readily obtained from the corresponding halogenated phenols in two steps, were identified as novel benzyne precursors. These species were converted to benzynes by a domino reaction of O-desilylation,
A domino process for benzyne preparation: Dual activation of o-(trimethylsilyl)phenols by nonafluorobutanesulfonyl fluoride
Ikawa, Takashi,Nishiyama, Tsuyoshi,Nosaki, Toshifumi,Takagi, Akira,Akai, Shuji
, p. 1730 - 1733 (2011/06/16)
Benzynes were generated from o-(trimethylsilyl)phenols using nonafluorobutanesulfonyl fluoride (NfF) by a domino process, i.e., the nonaflation of the phenolic hydroxyl group of o-(trimethylsilyl)phenols by NfF followed by the attack of the produced fluoride ion on the trimethylsilyl group. The generated benzyne immediately underwent various reactions to give polysubstituted benzenes.
