127634-96-2

Basic information

• Product Name: 3-Methyl-2-phenyl-morpholine-4-carboxylic acid ethyl ester
• Synonyms: 3-Methyl-2-phenyl-morpholine-4-carboxylic acid ethyl ester
• CAS NO: 127634-96-2
• Molecular Weight: 249.31
• Mol File: 127634-96-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-Methyl-2-phenyl-morpholine-4-carboxylic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Methyl-2-phenyl-morpholine-4-carboxylic acid ethyl ester(127634-96-2)
• EPA Substance Registry System: 3-Methyl-2-phenyl-morpholine-4-carboxylic acid ethyl ester(127634-96-2)

Safety Data

• Hazardous Substances Data: 127634-96-2(Hazardous Substances Data)

Upstream product

• 21784-30-5 phendimetrazine 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 1707-14-8 phenmetrazine hydrochloride 

Relevant articles and documents

Synthesis, toxicological, and pharmacological assessment of derivatives of 2-aryl-4-(3-arylpropyl)morpholines

The synthesis of nine original morpholine derivatives, i.e.2-aryl-4-(3- arylpropyl)morpholines, is described. The structure of all synthesised derivatives was proved by IR and 1H-NMR, and some of them by 13C-NMR. Acute toxicity studies of the compounds were performed on mice. A comparative pharmacological study of the in vivo effects on the central nervous system was undertaken using the screening tests: hexobarbital induced sleeping time; locomotor activity; and behaviour despair (for antidepressive activity). The most active compound 4-(2-benzoylethyl)-2-phenyl-3-methyl) morpholine 4e was studied for MAO-A and MAO-B inhibition in vitro in rat brain mitochondria preparations.