1277188-80-3

Basic information

• Product Name: (2S,4R)-6-bromo-3,4-dihydro-2,4-diphenyl-2H-1-benzopyran-4-ol
• Synonyms: (2S,4R)-6-bromo-3,4-dihydro-2,4-diphenyl-2H-1-benzopyran-4-ol
• CAS NO: 1277188-80-3
• Molecular Weight: 381.269
• Mol File: 1277188-80-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,4R)-6-bromo-3,4-dihydro-2,4-diphenyl-2H-1-benzopyran-4-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4R)-6-bromo-3,4-dihydro-2,4-diphenyl-2H-1-benzopyran-4-ol(1277188-80-3)
• EPA Substance Registry System: (2S,4R)-6-bromo-3,4-dihydro-2,4-diphenyl-2H-1-benzopyran-4-ol(1277188-80-3)

Safety Data

• Hazardous Substances Data: 1277188-80-3(Hazardous Substances Data)

Upstream product

• 51483-92-2 6-bromo-1-benzopyran-4(4H)-one 
• 98-80-6 phenylboronic acid 

Relevant articles and documents

Highly enantioselective and efficient synthesis of flavanones including pinostrobin through the rhodium-catalyzed asymmetric 1,4-addition

An efficient synthesis of bioactive chiral flavanones (1) was achieved through the αh-catalyzed asymmetric 1,4-addition of arylboronic acid to chromone. The reaction in toluene proceeded smoothly at room temperature in the presence of 0.5% Rh catalyst with electron-poor chiral diphosphine MeO-F 12-BIPHEP. In this reaction, the 1,2-addition to (S)-1 frequently occurred to yield (2S,4α)-2,4-diaryl-4-chromanol as a byproduct, which could be reduced by changing the reaction solvent to CH2C 12 to deactivate the Rh catalyst (3% required).