1277239-97-0Relevant articles and documents
Biarylmethoxy isonipecotanilides as potent and selective inhibitors of blood coagulation factor Xa
Lopopolo, Gianfranco,Fiorella, Filomena,De Candia, Modesto,Nicolotti, Orazio,Martel, Sophie,Carrupt, Pierre-Alain,Altomare, Cosimo
, p. 180 - 191 (2012/01/05)
New chloro-substituted biarylmethoxyphenyl piperidine-4-carboxamides were synthesized and assayed in vitro as inhibitors of the blood coagulation enzymes factor Xa (fXa) and thrombin. An investigation of effects of the amidine and isopropyl groups attache