127727-92-8Relevant articles and documents
TRANS-NITRILATION IN THE SERIES OF 2-ALKENOIC ACIDS
Polivin, Yu. N.,Karakhanov, R. A.,Vinokurov, V. A.,Mikaya, A. I.,Silin, M. A.,Makarshin, S. V.
, p. 1795 - 1798 (2007/10/02)
In the case of the reaction of trans-2-hexenoic acid with acetonitrile it was established that acids of the olefinic series enter into trans-nitrilation with aliphatic nitriles; the reaction is complicated by thermal isomerization both of the initial acid and of the reaction products, i.e., the corresponding nitrile and N-acylamide.Under the conditions of the reaction of trans-2-hexenoic acid with deuteroacetonitrile-d3 1,3-hydride-deuteride shifts occur in the intermediate compounds (the N-acylamides).This leads to a redistribution of the deuterium atoms between the products of the investigated reaction.
