127841-01-4Relevant articles and documents
2,3'-DIFLUORO- AND 3'-AZIDO-2'-FLUORO SUBSTITUTED DIDEOXYPYRIMIDINES AS POTENTIAL ANTI-HIV AGENTS
Aerschot, A. Van,Herdewijn, P.
, p. 937 - 942 (2007/10/02)
2'-Deoxy-2'-fluorouridine (2) was obtained by reaction of the arabinofuranosyl nucleoside 1 with diethylaminosulfur trifluoride followed by detritylation.After inversion of the configuration at the 3'-position, 4 was used as starting material for the preparation of the 2',3'-disubstituted derivatives 6, 7, 8 and 10.