127852-78-2

Basic information

• Product Name: Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (S)- (9CI)
• Synonyms: Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (S)- (9CI);(S)-4-(Boc-amino)-4-hydroxybutyric acid;(S)-4-((tert-Butoxycarbonyl)amino)-3-hydroxybutanoic acid
• CAS NO: 127852-78-2
• Molecular Formula: C9H17NO5
• Molecular Weight: 219.23498
• Product Categories: N-BOC
• Mol File: 127852-78-2.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 411.8±40.0 °C(Predicted)
• Appearance: /
• Density: 1.204±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 4.30±0.10(Predicted)
• CAS DataBase Reference: Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (S)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (S)- (9CI)(127852-78-2)
• EPA Substance Registry System: Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (S)- (9CI)(127852-78-2)

Safety Data

• Hazardous Substances Data: 127852-78-2(Hazardous Substances Data)

Usage

General Description

The chemical "Butanoic acid, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-3-hydroxy-, (S)- (9CI)" is a specific stereoisomer of a compound made up of butanoic acid, a carbonyl group, an amino group, and a hydroxy group. It is classified as an amino acid derivative, specifically a hydroxyamino acid, and is often used in the pharmaceutical industry as a building block for the synthesis of various drugs and compounds. The specific stereochemistry of this compound (S)-configuration) is important for its biological activity and interactions with other molecules in the body. This chemical has the potential for application in drug development and research.

Upstream product

• 7013-05-0 (S)-4-amino-3-hydroxybutanoic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 924-49-2 DL-4-amino-3-hydroxybutyric acid 
• 847599-34-2 4-benzyloxy-1-tert-butyl-pyrrolidin-2-one 
• 181772-51-0 ethyl (3R)-4-(tert-butyloxycarbonyl)amino-3-hydroxybutanoate 
• 119960-04-2 methyl 4-[(tert-butoxycarbonyl)amino]-3-oxobutanoate 
• 4530-20-5 BOC-glycine 
• 34619-03-9 tert-butyldicarbonate 
• 87554-49-2 (R)-(-)-methyl N-t-butyloxycarbonyl-3-hydroxy-4-aminobutanoate 

Relevant articles and documents

A paradigm for solvent and temperature induced conformational changes

The complex conformational dependency on environment of Boc-amine (see scheme) has been investigated. This model organic molecule has many features applicable to areas of chemistry, biology, physics, and computational chemistry. It is soluble in both non-polar and polar solvents, conformationally heterogeneous, and capable of supramolecular assembly. Copyright

SUBSTITUTED 1,1'-BIPHENYL COMPOUNDS AND METHODS USING SAME

The present invention includes substituted 1,1'-biphenyl compounds, analogues thereof, and compositions comprising the same. In one aspect, the compounds contemplated in the invention can be used to treat, ameliorate, or prevent hepatitis B virus (HBV) and/or hepatitis D virus (HDV) infections in a patient. In another aspect, the compounds contemplated in the invention can be used to treat, ameliorate, and/or prevent cancer in a patient.

DIHYDROPYRROLE DERIVATIVES AS INSECTICIDAL COMPOUNDS

The present invention provides compounds of formula (I), wherein G1 is oxygen; R1 is hydrogen; R2 is group P L is a bond, methylene or ethylene; one of A1 and A2 is S, SO or S02 and the other is -C(R4)R4- R3 is hydrogen or methyl; each R4 is independently hydrogen or methyl; Y1 is C-R6, CH or nitrogen; Y2 and Y3 are independently CH or nitrogen; wherein no more than two of Y1, Y2 and Y3 are nitrogen and wherein Y2 and Y3 are not both nitrogen; R5 is hydrogen, halogen, cyano, nitro, NH2, -C2alkyl, C3-C2haloalkyl, C3-C5cycloalkyl, C3- C5halocycloalkyl, C1-C2alkoxy, C1-C2haloalkoxy; R6 together with R5 forms a -CH=CH-CH=CH- bridge; X2 is C-X6 or nitrogen; X1, X3 and X6 are independently hydrogen, halogen or trihalomethyl, wherein at least two of X1, X3 and X6 are not hydrogen; X4 is trifluoromethyl, difluoromethyl or chlorodifluoromethyl. The invention also provides intermediates useful for the preparation of compounds of formula I, as well as methods of controlling insects, acarines, nematodes or molluscs using the compounds of formula I.