127926-10-7 Usage
Description
(1R,2S)-7-methyl-1,2-dihydronaphthalene-1,2-diol, also known as 7-Methyl-1,2-dihydro-1,2-naphthalenediol, is a chiral chemical compound with the molecular formula C11H14O2. It is a derivative of naphthalene and features a diol functional group. The (1R,2S) designation indicates the configuration of its stereocenters, making it a chiral molecule. (1R,2S)-7-methyl-1,2-dihydronaphthalene-1,2-diol is used in organic synthesis and can be found in various natural products. Its unique structure and potential applications in the pharmaceutical and agrochemical industries make it an interesting target for chemical research and development. Furthermore, its chirality makes it a valuable tool for the study of stereochemistry and chiral separation techniques.
Uses
Used in Organic Synthesis:
(1R,2S)-7-methyl-1,2-dihydronaphthalene-1,2-diol is used as a building block in organic synthesis for the creation of various complex organic molecules. Its unique structure and functional groups make it a versatile compound for constructing pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (1R,2S)-7-methyl-1,2-dihydronaphthalene-1,2-diol is used as an intermediate in the synthesis of drug candidates. Its chiral nature allows for the development of enantiomerically pure compounds, which can exhibit different biological activities and reduce potential side effects.
Used in Agrochemical Industry:
(1R,2S)-7-methyl-1,2-dihydronaphthalene-1,2-diol is also used in the agrochemical industry as a precursor for the development of new pesticides and other agricultural chemicals. Its unique structure can contribute to the creation of novel and more effective products.
Used in Chemical Research and Development:
Due to its unique structure and potential applications, (1R,2S)-7-methyl-1,2-dihydronaphthalene-1,2-diol is used as a target compound in chemical research and development. It can help scientists explore new reaction pathways, develop innovative synthetic methods, and discover new applications for this compound.
Used in Stereochemistry and Chiral Separation Techniques:
The chirality of (1R,2S)-7-methyl-1,2-dihydronaphthalene-1,2-diol makes it a valuable tool for studying stereochemistry and chiral separation techniques. It can be used to develop new methods for the separation of enantiomers, which is crucial for the production of enantiomerically pure compounds in various industries, including pharmaceuticals and agrochemicals.
Check Digit Verification of cas no
The CAS Registry Mumber 127926-10-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,7,9,2 and 6 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 127926-10:
(8*1)+(7*2)+(6*7)+(5*9)+(4*2)+(3*6)+(2*1)+(1*0)=137
137 % 10 = 7
So 127926-10-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H12O2/c1-7-2-3-8-4-5-10(12)11(13)9(8)6-7/h2-6,10-13H,1H3/t10-,11+/m0/s1
127926-10-7Relevant articles and documents
Toluene dioxygenase-catalyzed synthesis of cis-dihydrodiol metabolites from 2-substituted naphthalene substrates: Assignments of absolute configurations and conformations from circular dichroism and optical rotation measurements
Kwit, Marcin,Gawronski, Jacek,Boyd, Derek R.,Sharma, Narain D.,Kaik, Magdalena,More O'Ferrall, Rory A.,Kudavalli, Jaya S.
scheme or table, p. 11500 - 11511 (2009/12/03)
cis-Dihydrodiol metabolites have been isolated from naphthalene and six 2-substituted naphthalene substrates. Their structures and absolute configurations have been determined by a combination of calculated (TDDFT) and experimentally based circular dichroism (CD) and optical rotation (OR) methods. The inverse styrene helicity rule is shown to be incorrect for the interpretation of theCD spectra of cis-dihydrodiols. A striking conclusion is that CD spectra correlate directly with the helicity of the styrene chromophore: that is, the sign of the long-wavelength Cotton effect is identical with the sign of styrene torsion angle, whereas the OR sign is dependent on the absolute configuration of the allylic carbon atom. The results demonstrate that a predictive model previously used for the determination of preferred regio- and stereoselectivity associated with TDO-catalyzed cis-dihydroxylation of substituted benzene substrates can now be successfully extended to substituted naphthalene substrates.
