128049-47-8

Basic information

• Product Name: (+)-(3S)-6-(benzyloxy)-1-((tert-butyloxy)carbonyl)-3-(hydroxymethyl)indoline
• Synonyms: (+)-(3S)-6-(benzyloxy)-1-((tert-butyloxy)carbonyl)-3-(hydroxymethyl)indoline
• CAS NO: 128049-47-8
• Molecular Weight: 355.434
• Mol File: 128049-47-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (+)-(3S)-6-(benzyloxy)-1-((tert-butyloxy)carbonyl)-3-(hydroxymethyl)indoline(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(3S)-6-(benzyloxy)-1-((tert-butyloxy)carbonyl)-3-(hydroxymethyl)indoline(128049-47-8)
• EPA Substance Registry System: (+)-(3S)-6-(benzyloxy)-1-((tert-butyloxy)carbonyl)-3-(hydroxymethyl)indoline(128049-47-8)

Safety Data

• Hazardous Substances Data: 128049-47-8(Hazardous Substances Data)

Upstream product

• 119879-94-6 5-(benzyloxy)-2-bromo-N-((tert-butyloxy)carbonyl)-N-(4-(phenylthio)-2-buten-1-yl)aniline 
• 119879-92-4 5-(benzyloxy)-2-bromo-N-((tert-butyloxy)carbonyl)aniline 
• 119879-90-2 5-(Benzyloxy)-2-bromophenylamine 
• 1484-26-0 3-(benzyloxy)aniline 
• 24424-99-5 di-tert-butyl dicarbonate 
• 184046-62-6 Acetic acid (S)-6-benzyloxy-2,3-dihydro-1H-indol-3-ylmethyl ester 
• 184046-60-4 Acetic acid (S)-2-(4-benzyloxy-2-nitro-phenyl)-3-hydroxy-propyl ester 
• 106014-83-9 2-[4-(benzyloxy)-2-nitrophenyl]propane-1,3-diol 
• 119879-96-8 6-(benzyloxy)-1-((tert-butyloxy)carbonyl)-3-vinylindoline 

Relevant articles and documents

Synthesis and evaluation of the hybrid molecules possessing DNA-cleaving activity

The design and synthesis of enantiomerically enriched hybrid molecules, 1a-c and 2a-c, have been accomplished by employing the lipase-mediated asymmetric acetylation of prochiral diol 9 as the key step. Evaluation of their DNA-cleaving activity has revealed the unnatural type of enantiomer 2a-c to be more potent than 1a-c with natural configuration.