1280551-80-5Relevant articles and documents
Highly efficient total synthesis of the clostridium-derived anti-MRSA antibiotic closthioamide
Kloss, Florian,Lincke, Thorger,Hertweck, Christian
, p. 1429 - 1431 (2011)
The antibiotic closthioamide from Clostridium cellulolyticum, the first example of a secondary metabolite from strictly anaerobic bacteria, was synthesized by a versatile and highly efficient synthetic route. This starts from simple building blocks and involves convergent peptide coupling and polythionation. The antibiotic closthioamide from Clostridium cellulolyticum, the first example of a secondary metabolite from strictly anaerobic bacteria, was synthesized by a versatile and highly efficient route starting from simple building blocks, involving convergent peptide coupling and polythionation. Copyright
