128071-79-4

Basic information

• Product Name: 2-Fluoro-4-Bromo-3-Picoline
• Synonyms: 2-Fluoro-4-Bromo-3-Picoline;4-Bromo-2-fluoro-3-methylpyridine;4-BROMO-2-FLUORO-3-METHYLPYRIDIN
• CAS NO: 128071-79-4
• Molecular Formula: C₆H₅BrFN
• Molecular Weight: 190.0130032
• Product Categories: Pyridine
• Mol File: 128071-79-4.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 220℃
• Flash Point: 87℃
• Appearance: /
• Density: 1.592
• Vapor Pressure: 0.17mmHg at 25°C
• Refractive Index: 1.529
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• PKA: 1.05±0.10(Predicted)
• CAS DataBase Reference: 2-Fluoro-4-Bromo-3-Picoline(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Fluoro-4-Bromo-3-Picoline(128071-79-4)
• EPA Substance Registry System: 2-Fluoro-4-Bromo-3-Picoline(128071-79-4)

Safety Data

• RIDADR: UN1993
• Hazardous Substances Data: 128071-79-4(Hazardous Substances Data)

Usage

General Description

2-Fluoro-4-Bromo-3-Picoline is a chemical compound with the molecular formula C6H4BrFN. It is a halogenated pyridine derivative that is used in the pharmaceutical industry as a building block for the synthesis of various pharmaceutical compounds. This chemical is a clear, colorless liquid with a pungent odor, and it is primarily utilized in the production of agricultural products, pharmaceuticals, and chemical research. It is known for its high purity and stability, making it a valuable reagent in chemical processes. Additionally, 2-Fluoro-4-Bromo-3-Picoline is also used in scientific research and as a precursor in the development of new chemical compounds.

InChI:InChI=1/C6H5BrFN/c1-4-5(7)2-3-9-6(4)8/h2-3H,1H3

Upstream product

• 372-48-5 2-fluoropyridine 
• 74-88-4 methyl iodide 
• 128071-98-7 4-bromo-2-fluoropyridine 

Downstream Products

• 7631-86-9 SiO₂ 

Relevant articles and documents

INHIBITORS OF INDOLEAMINE 2,3-DIOXYGENASE AND METHODS OF THEIR USE

There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.

Migration du lithium en serie pyridinique: double catalyse et reformage. Acces aux derives de la bromo-2 lithio-3 pyridine et des bromo-4 halogeno-2 lithio-3 pyridines

The lithium of an organolithium-pyridinic derivative can be moved from one position to an another by an intermolecular reaction.Two new reactions are possible for pyridinic organic synthesis: the isomerisation of any lithio derivative to a more stable one, and a reaction that transforms a mixture of various bromo-lithio derivatives into a single one.The processes involved and the experimental tools used are described in terms of the 2-bromo-3-lithio- and 4-bromo-2-halogeno-3-lithiopyridines derivatives synthesis.