128318-02-5Relevant articles and documents
Synthesis of panaxytriol and its stereoisomers as potential antitumor drugs
Mao, Jianyou,Zhong, Jiangchun,Wang, Bo,Jin, Jing,Li, Shuoning,Gao, Zidong,Yang, Hanze,Bian, Qinghua
, p. 330 - 337 (2016/04/09)
An efficient synthesis of panaxytriol and its seven stereoisomers was achieved, and four unnatural diastereomers of 2a were prepared. The key steps involved the opening of vicinal hydroxy epoxides, the stereospecific opening of the epoxides with perchlori
Syntheses of two diastereoisomers of panaxytriol, a potent antitumor agent isolated from Panax ginseng
Lu, Wei,Zheng, Guangrong,Gao, Daxin,Cai, Junchao
, p. 7157 - 7168 (2007/10/03)
(3R, 9R, 10R) and (3R, 9S, 10S) diastereoisomers (2 and 3) of panaxytriol (1) were synthesized, and the absolute configuration of panaxytriol was confirmed as (3R, 9R, 10R)-heptadec-1-ene-4,6-diyne-3,9,10- triol.