128345-62-0 Usage
Description
Ranitidine bismuth citrate is a novel salt formed from ranitidine and a bismuth citrate complex, designed for the treatment of duodenal and benign gastric ulcers, eradication of Helicobacter pylori, and prevention of duodenal ulcer relapse when combined with antibiotics like clarithromycin or amoxicillin. It is a potent histamine H2-receptor antagonist that inhibits gastric acid secretion and combines the properties of both H2-receptor antagonists and bismuth-based agents, displaying excellent therapeutic efficacy in clinical studies.
Uses
Used in Pharmaceutical Industry:
Ranitidine bismuth citrate is used as an active pharmaceutical ingredient for the treatment of duodenal and benign gastric ulcers, eradication of Helicobacter pylori, and prevention of duodenal ulcer relapse when administered in combination with an antibiotic such as clarithromycin or amoxicillin.
Used in Gastroenterology:
Ranitidine bismuth citrate is used as a therapeutic agent for gastritis and non-ulcerating dyspepsia, acute healing of gastrointestinal ulcers, and prevention of the recurrence of peptic ulcer disease.
Brand Names:
Tritec (GlaxoSmithKline) and Pylorid.
Hazard
A poison by ingestion.
Check Digit Verification of cas no
The CAS Registry Mumber 128345-62-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,3,4 and 5 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 128345-62:
(8*1)+(7*2)+(6*8)+(5*3)+(4*4)+(3*5)+(2*6)+(1*2)=130
130 % 10 = 0
So 128345-62-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H22N4O3S.C6H8O7.Bi/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3;7-3(8)1-6(13,5(11)12)2-4(9)10;/h4-5,9,14-15H,6-8,10H2,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);/q;;+3/p-3/b13-9-;;
