128359-99-9

Basic information

• Product Name: (2S)-1-(Benzyloxycarbonyl)-2-<<(tert-butyldimethylsilyl)oxy>methyl>pyrrolidine
• Synonyms: (2S)-1-(Benzyloxycarbonyl)-2-<<(tert-butyldimethylsilyl)oxy>methyl>pyrrolidine
• CAS NO: 128359-99-9
• Molecular Weight: 349.546
• Mol File: 128359-99-9.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: (2S)-1-(Benzyloxycarbonyl)-2-<<(tert-butyldimethylsilyl)oxy>methyl>pyrrolidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2S)-1-(Benzyloxycarbonyl)-2-<<(tert-butyldimethylsilyl)oxy>methyl>pyrrolidine(128359-99-9)
• EPA Substance Registry System: (2S)-1-(Benzyloxycarbonyl)-2-<<(tert-butyldimethylsilyl)oxy>methyl>pyrrolidine(128359-99-9)

Safety Data

• Hazardous Substances Data: 128359-99-9(Hazardous Substances Data)

Upstream product

• 59936-29-7 (S)-N-(tert-butoxycarbonyl)proline methyl ester 
• 69610-40-8 N-(tert-butoxycarbonyl)-L-prolinol 
• 6216-63-3 N-Cbz-Prolinol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 153870-09-8 (S)-1-(benzyloxycarbonyl)-5-[(tert-butyldimethylsilyl)oxymethyl]-2-pyrrolidinone 

Downstream Products

• 134756-75-5 (2S)-2-({[(tert-butyl)(dimethyl)silyl]oxy}methyl)pyrrolidine 

Relevant articles and documents

Total synthesis of (-)-domoic acid. A revision of the original structure

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Lewis acid-induced internal proton return in enolate complexes with chiral amines

Treatment of a 1:1:1 mixture of enolate 5:amine 6:lithium amide 7 with BF3·OEt2 affords the naproxen amide 4a with an enantiomer excess of 77% (>90% yield). The result is attributed to Lewis acid-induced internal proton return (ipr)

Selective Transformation of O-2-(Trimethylsilyl)ethyl and O-tert-Butyl Carbamates into O-Benzyl Carbamates Using Benzyl Trichloroacetimidate

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