128425-14-9

Basic information

• Product Name: D-Proline, 1-[5-[(2-amino-1-methyl-2-oxoethyl)amino]-2,4-dinitrophenyl]-, (S)-
• CAS NO: 128425-14-9
• Molecular Formula: C14H17N5O7
• Molecular Weight: 367.318
• Mol File: 128425-14-9.mol
• Article Data: 27

Chemical Properties

• CAS DataBase Reference: D-Proline, 1-[5-[(2-amino-1-methyl-2-oxoethyl)amino]-2,4-dinitrophenyl]-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: D-Proline, 1-[5-[(2-amino-1-methyl-2-oxoethyl)amino]-2,4-dinitrophenyl]-, (S)-(128425-14-9)
• EPA Substance Registry System: D-Proline, 1-[5-[(2-amino-1-methyl-2-oxoethyl)amino]-2,4-dinitrophenyl]-, (S)-(128425-14-9)

Safety Data

• Hazardous Substances Data: 128425-14-9(Hazardous Substances Data)

Upstream product

• 1236074-94-4 trichoderin A 
• 95713-52-3 N-(2,4-dinitro-5-fluorophenyl)-L-alaninamide 
• 1236074-95-5 trichoderin A₁ 
• 1236074-96-6 trichoderin B 
• 32021-26-4 3-benzylhexahydropyrrolo[1,2-a]pyrazin-1,4-dione 
• 3705-27-9 (R)-(+)-1,4-diazabicyclo<4.3.0>nonane-2,5-dione 
• 149204-42-2 cyclo[L-Val(1)-Z-Dhb-L-Phe-D-Val(2)-D-allo-Ile(1)-D-allo-Thr(1)]-D-allo-Ile(2)-L-Orn-D-Pro-D-Val(3)-L-Val(4)-L-Thr(2)-D-Val(5)-5-MeHex 
• 639819-39-9 C₆₃H₁₀₃N₁₃O₁₄ 
• 1198473-27-6 5-OHKF 
• 344-25-2 D-Prolin 
• 609-36-9 rac-Pro-OH 

Relevant articles and documents

Bromophenol coupled with diketopiperazine from marine red alga symphyocladia latiuscula

2-(2,3,6-Tribromo-4,5-dihydroxybenzyl)hexahydropyrrolo[1,2-a]pyrazine-1, 4-dione (1), a new bromophenol C-N coupled with diketopiperazine, was isolated from the ethanol extract of marine red alga Symphyocladia latiuscula. Its structure was elucidated by s

Cyclic tetrapeptides from the marine strain Streptomyces sp. PNM-161a with activity against rice and yam phytopathogens

Two cyclotetrapeptides, henceforth named Provipeptides A (1) and B (2), along with five known diketopiperazines (3–7) were isolated from the liquid culture of marine Streptomyces sp. 161a recovered from a sample of sea grass Bryopsis sp. The structures of cyclotetrapeptides and diketopiperazines (DKPs) were established by 1D and 2D NMR data, MS, and by comparison with literature data. The absolute stereochemistry of compounds cyclo-(l-Pro-l-Leu-d-Pro-l-Phe) 1 and cyclo-(-Pro-Ile-Pro-Phe) 2 was established by the Marfey’s method. Compound 1 showed antibacterial activity against rice phytopathogenic strains Burkholderia glumae (MIC = 1.1 mM) and Burkholderia gladioli (MIC = 0.068 mM), compound 2 was active only against B. glumae (MIC = 1.1 mM), and DKP cyclo-[l-Pro-l-Leu] 5 showed to be active against B. gladioli (MIC = 0.3 mM) and B. glumae (MIC = 2.4 mM). Compounds 1 and 2 showed 65% and 50% inhibition of Colletotrichum gloeosporioides (yam pathogen) conidia germination, respectively at a concentration of 1.1 mM.

Cytotoxic and antimicrobial compounds from the marine-derived fungus, penicillium species

The organic extract of liquid cultures of the marine-derived Penicillium sp. was investigated. Fractionation of the extracts of the fungus led to the purification and identification of two new compounds, penicillatides A (1) and B (2), together with the previously reported cyclo(R-Pro–S-Phe) (3) and cyclo(R-Pro–R-Phe) (4). The structures of compounds 1–4 were assigned by extensive interpretation of their NMR and high-resolution mass spectrometry (HRMS). The antiproliferative and cytotoxic activities of the compounds against three human cancer cell lines as well as their antimicrobial activity against several pathogens were evaluated. Compounds 2–4 displayed variable cytotoxic and antimicrobial activities.