128488-31-3

Basic information

• Product Name: (2R,3R)-5-(2-Dimethylamino-ethyl)-2-ethyl-3-hydroxy-2-(4-methoxy-phenyl)-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one
• CAS NO: 128488-31-3
• Molecular Weight: 400.542
• Mol File: 128488-31-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R)-5-(2-Dimethylamino-ethyl)-2-ethyl-3-hydroxy-2-(4-methoxy-phenyl)-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-5-(2-Dimethylamino-ethyl)-2-ethyl-3-hydroxy-2-(4-methoxy-phenyl)-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one(128488-31-3)
• EPA Substance Registry System: (2R,3R)-5-(2-Dimethylamino-ethyl)-2-ethyl-3-hydroxy-2-(4-methoxy-phenyl)-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one(128488-31-3)

Safety Data

• Hazardous Substances Data: 128488-31-3(Hazardous Substances Data)

Upstream product

• 128488-07-3 (2R,3R)-4-Ethoxy-2-ethyl-2-(4-methoxy-phenyl)-2,3-dihydro-benzo[b][1,4]thiazepin-3-ol 
• 128487-99-0 2-Ethyl-2-(4-methoxy-phenyl)-5H-benzo[b][1,4]thiazepine-3,4-dione 
• 27068-88-8 3c-hydroxy-2r-(4-methoxy-phenyl)-2,3-dihydro-5H-benzo[b][1,4]thiazepin-4-one 
• 4584-46-7 (2-chloroethyl)dimethylamine hydrochloride 
• 128488-02-8 (2RS,3RS)-2-ethyl-2,3-dihydro-3-hydroxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 
• 128487-88-7 3-acetoxy-4-ethoxy-2-(4-methoxyphenyl)-1,5-benzothiazepine 
• 128487-91-2 (RS)-2-ethyl-4-ethoxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-3(2H)-one 
• 97801-78-0 3-acetoxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one 

Relevant articles and documents

SYNTHESIS OF 2-SUBSTITUTED DERIVATIVES OF DILTIAZEM

Titled compounds, 2a,b,c,d and e, were efficiently synthesized from 3-acetoxy-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one (4) through alkylation at the C2- position followed by stereoselective reduction of the C3- carbonyl group.