128540-49-8

Basic information

• Product Name: Benzamide, 3,4,5-trimethoxy-N-[[4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]methyl]-
• CAS NO: 128540-49-8
• Molecular Formula: C24H33N3O5
• Molecular Weight: 443.543
• Mol File: 128540-49-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzamide, 3,4,5-trimethoxy-N-[[4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]methyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzamide, 3,4,5-trimethoxy-N-[[4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]methyl]-(128540-49-8)
• EPA Substance Registry System: Benzamide, 3,4,5-trimethoxy-N-[[4-[2-(4-methyl-1-piperazinyl)ethoxy]phenyl]methyl]-(128540-49-8)

Safety Data

• Hazardous Substances Data: 128540-49-8(Hazardous Substances Data)

Upstream product

• 118-41-2 Eudesmic acid 
• 128540-27-2 4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-benzaldehyde oxime; hydrochloride 
• 4521-61-3 3,4,5-Trimethoxybenzoyl chloride 
• 128540-39-6 4-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-benzylamine 

Relevant articles and documents

Synthesis, gastrointestinal prokinetic activity and structure-activity relationships of novel N-[[2-(dialkylamino)ethoxy]benzyl]benzamide derivatives

Novel N-[[2-(dialkylamino)ethoxy]benzyl]benzamide derivatives (II-1-51), derived from the structural modification of metoclopramide (1), were synthesized and examined for their pharmacological activities. Among them, N-[4-[2-(dimethylamino)ethoxy]benzyl]-3,4-dimethoxybenzamide (II-34) which exhibited well balanced gastrointestinal prokinetic and antiemetic activities was selected as a new type of gastrointestinal prokinetic agent.