128640-74-4 Usage
General Description
4-CHLORO-6-(4-METHYLPHENYL)-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE is a chemical compound that belongs to the pyrimidine family. It is a yellow solid that is insoluble in water but soluble in organic solvents. 4-CHLORO-6-(4-METHYLPHENYL)-2-(METHYLTHIO)PYRIMIDINE-5-CARBONITRILE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It has a wide range of applications in the field of medicine and agriculture, due to its ability to act as a building block for more complex molecules. Additionally, it is used as a reagent in chemical reactions to produce various derivatives for further research and development purposes.
Check Digit Verification of cas no
The CAS Registry Mumber 128640-74-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,8,6,4 and 0 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 128640-74:
(8*1)+(7*2)+(6*8)+(5*6)+(4*4)+(3*0)+(2*7)+(1*4)=134
134 % 10 = 4
So 128640-74-4 is a valid CAS Registry Number.
InChI:InChI=1/C13H10ClN3S/c1-8-3-5-9(6-4-8)11-10(7-15)12(14)17-13(16-11)18-2/h3-6H,1-2H3
128640-74-4Relevant articles and documents
Synthesis, antiplasmodial activity and mechanistic studies of pyrimidine-5-carbonitrile and quinoline hybrids
Kaur, Hardeep,Balzarini, Jan,De Kock, Carmen,Smith, Peter J.,Chibale, Kelly,Singh, Kamaljit
supporting information, p. 52 - 62 (2015/06/30)
Abstract A series of hybrids comprising of 5-cyanopyrimidine and quinoline moiety were synthesized and tested for in vitro antiplasmodial activity against NF54 and Dd2 strains of Plasmodium falciparum. Hybrid bearing m-nitrophenyl substituent at C-4 of py