128668-91-7

Basic information

• Product Name: (4aR,7aS)-3-(4-Chloro-phenyl)-hexahydro-cyclopentapyrimidine-2,4-dione
• Synonyms: (4aR,7aS)-3-(4-Chloro-phenyl)-hexahydro-cyclopentapyrimidine-2,4-dione
• CAS NO: 128668-91-7
• Molecular Weight: 264.711
• Mol File: 128668-91-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4aR,7aS)-3-(4-Chloro-phenyl)-hexahydro-cyclopentapyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (4aR,7aS)-3-(4-Chloro-phenyl)-hexahydro-cyclopentapyrimidine-2,4-dione(128668-91-7)
• EPA Substance Registry System: (4aR,7aS)-3-(4-Chloro-phenyl)-hexahydro-cyclopentapyrimidine-2,4-dione(128668-91-7)

Safety Data

• Hazardous Substances Data: 128668-91-7(Hazardous Substances Data)

Upstream product

• 104-12-1 p-chlorphenylisocyanate 
• 142-29-0 cyclopentene 
• 106-47-8 4-chloro-aniline 
• 22031-52-3 cis-2-aza-3-oxobicyclo<3.2.0>heptane 
• 57043-00-2 (1RS,2SR)-cispentacin 
• 125910-65-8 (1S,5R)-7-Oxo-6-aza-bicyclo[3.2.0]heptane-6-carboxylic acid (4-chloro-phenyl)-amide 
• 129193-15-3 (1R,2S)-2-Amino-cyclopentanecarboxylic acid (4-chloro-phenyl)-amide 

Relevant articles and documents

STEREOCHEMICAL STUDIES, 144. SATURATED HETEROCYCLES, 151. PREPARATION OF cis AND trans-CYCLOALKANE-CONDENSED PYRIMIDINEDIONES BY AZETIDINONE RING TRANSFORMATION

N-substituted derivatives (3 and 4) obtained from cyclopentane- and cyclohexane-azetidinones (1 and 2) were isomerized with polyphosphoric acid to give cyclopentane-cis- (6) and cyclohexane-trans-condensed (7) 2,4-pyrimidinediones.The structures of the dihydrouracils prepared by the ring transformation were proved by 1H- and 13C-nmr spectroscopy and by comparison with the compounds synthesized from cis- and trans-2-amino-1-cycloalkanecarboxamides (11-13) with 1,1'-carbonyldiimidazole.