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1286895-60-0

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1286895-60-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1286895-60-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,8,6,8,9 and 5 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1286895-60:
(9*1)+(8*2)+(7*8)+(6*6)+(5*8)+(4*9)+(3*5)+(2*6)+(1*0)=220
220 % 10 = 0
So 1286895-60-0 is a valid CAS Registry Number.

1286895-60-0Upstream product

1286895-60-0Relevant articles and documents

PYRROLIDINE DERIVATIVE OR SALT THEREOF

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Page/Page column 45, (2008/06/13)

[PROBLEMS] To provide a compound which can be used for the treatment of a disease associated with a calcium-sensing receptor (CaSR), particularly hyperparathyroidism. [MEANS FOR SOLVING PROBLEMS] It is found that a novel pyrrolidine derivative having an aminomethyl group substituted by an arylaklyl group or the like or a salt thereof has an excellent CaSR agonistic modulation effect and also has an excellent selectivity in the inhibition of CYP2D6 which may cause a drug-drug interaction. Thus, the novel pyrrolidine derivative is useful as a therapeutic agent for a disease associated with CaSR (e.g., hyperparathyroidism, renal osteodystrophy and hypercalcemia).

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