128813-45-6Relevant articles and documents
Development of an Alkyne Analogue of the de Mayo Reaction: Synthesis of Medium-Sized Carbacycles and Cyclohepta[b]indoles
Tymann, David,Tymann, Dina Christina,Bednarzick, Ulf,Iovkova-Berends, Ljuba,Rehbein, Julia,Hiersemann, Martin
, p. 15553 - 15557 (2018)
Embedded medium-sized carbacycles and cyclohepta[b]indoles occur frequently as scaffold elements in natural products and bioactive compounds. Described herein is a conceptionally novel photochemically triggered cascade process to these scaffolds. Key to the cascading ring-expansion process is an unprecedented intramolecular alkyne analogue of the de Mayo reaction.