128868-60-0

Basic information

• Product Name: 4-BROMOBENZOFURAN
• Synonyms: 4-BROMOBENZOFURAN;4-BroMobenzo[b]furan;4-BroMo-1-benzofuran;Benzofuran, 4-broMo-
• CAS NO: 128868-60-0
• Molecular Formula: C₈H₅BrO
• Molecular Weight: 197.04
• Product Categories: Aromatics;Heterocycles;Intermediates
• Mol File: 128868-60-0.mol
• Article Data: 21

Chemical Properties

• Boiling Point: 233.807°C at 760 mmHg
• Flash Point: 95.203°C
• Appearance: /
• Density: 1.608g/cm³
• Vapor Pressure: 0.084mmHg at 25°C
• Refractive Index: 1.639
• Storage Temp.: 2-8°C
• Solubility: Acetone, Chloroform, Ethyl Acetate
• CAS DataBase Reference: 4-BROMOBENZOFURAN(CAS DataBase Reference)
• NIST Chemistry Reference: 4-BROMOBENZOFURAN(128868-60-0)
• EPA Substance Registry System: 4-BROMOBENZOFURAN(128868-60-0)

Safety Data

• Hazardous Substances Data: 128868-60-0(Hazardous Substances Data)

Usage

Description

4-BROMOBENZOFURAN is a light yellow oil that serves as a key intermediate in the synthesis of various organic compounds, particularly in the preparation of aminoalkylbenzofurans.

Uses

Used in Pharmaceutical Industry:
4-BROMOBENZOFURAN is used as a chemical intermediate for the preparation of aminoalkylbenzofurans, which act as 5-HT2C agonists. These compounds have potential applications in the development of antiobesity and antidepressant medications, making them valuable in the pharmaceutical industry for addressing significant health concerns.

InChI:InChI=1/C8H5BrO/c9-7-2-1-3-8-6(7)4-5-10-8/h1-5H

Upstream product

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Downstream Products

• 325487-30-7 1-benzyl-3-methyl-4-hydroxy-4-(benzofuran-4-yl)piperidine 
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Relevant articles and documents

Five-membered heterocyclic oxo carboxylic acid compound and medical application thereof

The invention relates to a five-membered heterocyclic oxo carboxylic acid compound and a medical application thereof. Specifically, the invention relates to a compound, a pharmaceutical salt, a prodrug, a hydrate, a solvate or a crystal form as shown in a formula (I), and also relates to a preparation method of the compound, a pharmaceutical composition containing the compound and an application of the pharmaceutical composition as a secretion regulator of interferon type I, especially as an STING agonist in preparation of medicines for preventing and/or treating I-type interferon related diseases.

NAPHTHYRIDINE DERIVATIVES AS PRC2 INHIBITORS

Disclosed are compounds of formula (I) or (II) that inhibit Polycomb Repressive Complex 2 (PRC2) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.

Pyrimidine or pyrazino five-membered heterocyclic compound and applications thereof

The invention discloses a pyrimidine or pyrazino five-membered heterocyclic compound, a pharmaceutically acceptable salt, a hydrate, a prodrug, a stereoisomer or a solvate thereof, and provides a preparation method of the compound, a composition containing the compound, and applications of the compound in preparation of drugs for treating diseases or disorders related to the action mechanism of EED protein and/or PRC2 protein complex.