128878-80-8

Basic information

• Product Name: 7-amino-3-<5-O-(2-acetoxyisobutyryl)-3-deoxy-2-O-phenoxy(thiocarbonyl)-β-D-ribofuranosyl>-1H-pyrazolo<4,3-d>pyrimidine
• CAS NO: 128878-80-8
• Molecular Weight: 515.547
• Mol File: 128878-80-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-amino-3-<5-O-(2-acetoxyisobutyryl)-3-deoxy-2-O-phenoxy(thiocarbonyl)-β-D-ribofuranosyl>-1H-pyrazolo<4,3-d>pyrimidine(CAS DataBase Reference)
• NIST Chemistry Reference: 7-amino-3-<5-O-(2-acetoxyisobutyryl)-3-deoxy-2-O-phenoxy(thiocarbonyl)-β-D-ribofuranosyl>-1H-pyrazolo<4,3-d>pyrimidine(128878-80-8)
• EPA Substance Registry System: 7-amino-3-<5-O-(2-acetoxyisobutyryl)-3-deoxy-2-O-phenoxy(thiocarbonyl)-β-D-ribofuranosyl>-1H-pyrazolo<4,3-d>pyrimidine(128878-80-8)

Safety Data

• Hazardous Substances Data: 128878-80-8(Hazardous Substances Data)

Upstream product

• 40627-39-2 5'-O-(2-acetoxyisobutyryl)-3'-deoxyformycin A 
• 1005-56-7 phenylcarbonochloridothioate 

Downstream Products

• 40627-17-6 2',3'-dideoxyformycin A 

Relevant articles and documents

Synthesis of 2',3'-didehydro-2',3'-didoxyformycin A, 2',3'-Dideoxyformycin A and 2',3'-Dideoxytubercidin

2',3'-Didehydro-2',3'-dideoxyformycin A (7) was prepared by reaction of the 7-amino-3-[5-O-(2-acetoxyisobutyryl)-3-bromo-3-deoxy-2-O- phenoxy(thiocarbonyl)-β-D-xylofuranosyl]-1 H-pyrazolo [4,3-d]-pyrimidine (5) or 7-amino-3-[5-O-(2-acetoxyisobutyryl)-2- bromo-2-deoxy-3-O-phenoxy(thiocarbonyl)-β-D-arabinofuranosyl]-1 H-pyrazolo[4,3-d]pyrimidine (9) with tributyltin hydride and subsequent deprotection of the resulting 5'-O-(2-acetoxyisobutyryl)-2',3'-didehydro-2',3'-dideoxyformycin A (6). 2',3'-Dideoxyformycin A (13) and 2',3'-dideoxytubercidin (16) were synthesized via deoxygeneration of their respective 3'-deoxy counterparts 10 and 2, respectively.