128879-59-4Relevant articles and documents
Strategies and methods for the attachment of amino acids and peptides to chiral [n]polynorbornane templates.
Pfeffer, Frederick M,Russell, Richard A
, p. 1845 - 1851 (2007/10/03)
A versatile synthesis of amino acid and peptide functionalised [n]polynorbornane scaffolds is described. The frameworks are constructed using the stereoselective and regioselective cycloaddition of suitably functionalised chiral cyclobutene epoxides with similar norbornenes. The strategies employed allow a range of topologies to be accessed and a number of regioselectively addressable linkage points to be accommodated.
Synthesis and Photochemistry of Heterocyclic Norbornenyl Ketones
Sauers, R. R.,Hagedorn, A. A.,Arnum, S. D. Van,Gomez, R. P.,Moquin, R. V.
, p. 5501 - 5505 (2007/10/02)
A series of endo-5-norbonenyl ketones 1 was prepared which contained the following heterocyclic rings: 2-furyl, 2-thienyl, N-methyl-2-pyrryl, 3,5-dimethyl-4-isoxazolyl, 5-methyl-3-isoxazolyl and 2,5-dimethyl-4-oxazolyl groups.Oxetanes 2 were produced from the ketones either by direct irradiation (λ > 300 nm) or by use of photosensitizers.The two isoxazolyl systems were irradiated at 254 nm and found to lead to additional products, two of which were identified as 2H-azirines 16.It is probable that the latter were formed from an upper level excited state.
