128972-02-1Relevant articles and documents
5-(HETEROCYCLYLALKANOYL)AMINO-4-HYDROXYPENTANAMIDES
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, (2008/06/13)
This invention concerns novel nitrogen derivatives of the formula I STR1 (and their pharmaceutically-acceptable salts), together with pharmaceutical compositions containing them. The nitrogen derivatives are inhibitors of the catalytic action of renin. Th
AN EFFICIENT SYNTHESIS OF 3-ALKYL-5-ARYL-2(1H)-PYRAZINONES
Bradbury, Robert H.,Griffiths, David,Rivett, Janet E.
, p. 1647 - 1653 (2007/10/02)
The preparation of several 3-alkyl-5-aryl-2(1H)-pyrazinones is described.The regiochemical outcome of the condensation reaction between amine acid amides and phenylglyoxal is discussed and alternative, more efficient route is reported, involving ring-clos