129-90-8

Basic information

• Product Name: 8-p-toluidinonaphthalene-1-sulphonic acid
• Synonyms: 8-p-toluidinonaphthalene-1-sulphonic acid;8-(P-toluidino)naphthalene-1-sulfonic acid;Tolyl peri acid;8-(4-Aminotoluene)-1-naphthalenesulfonic acid;1-(p-Tolylamino)-8-naphthalenesulfonic acid;N-p-Tolyl-peri acid;8-(4-methylanilino)naphthalene-1-sulfonic acid;8-[(4-methylphenyl)amino]naphthalene-1-sulfonic acid
• CAS NO: 129-90-8
• Molecular Formula: C₁₇H₁₅NO₃S
• Molecular Weight: 313.3709
• EINECS: 204-968-7
• Mol File: 129-90-8.mol
• Article Data: 1

Chemical Properties

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.37g/cm³
• Refractive Index: 1.692
• CAS DataBase Reference: 8-p-toluidinonaphthalene-1-sulphonic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 8-p-toluidinonaphthalene-1-sulphonic acid(129-90-8)
• EPA Substance Registry System: 8-p-toluidinonaphthalene-1-sulphonic acid(129-90-8)

Safety Data

• Hazardous Substances Data: 129-90-8(Hazardous Substances Data)

Usage

General Description

8-p-toluidinonaphthalene-1-sulphonic acid, also known as 8-TNS, is a fluorescent dye commonly used in biochemical and pharmaceutical research. It has a molecular formula of C17H15NO3S and a molar mass of 317.37 g/mol. 8-TNS is soluble in water, alcohol, and ether and has a strong absorption peak at 340 nm and an emission peak at 449 nm, making it suitable for use in fluorescence microscopy and flow cytometry. It is commonly employed as a pH probe and as a fluorescent indicator for the determination of protein conformational changes. Additionally, 8-TNS is used in the study of the binding and transport of solutes in biological membranes and has applications in the food industry for the detection of contaminants. Due to its versatile and valuable properties, 8-p-toluidinonaphthalene-1-sulphonic acid is widely utilized in various scientific and industrial fields.

InChI:InChI=1/C17H15NO3S/c1-12-8-10-14(11-9-12)18-15-6-2-4-13-5-3-7-16(17(13)15)22(19,20)21/h2-11,18H,1H3,(H,19,20,21)

Upstream product

• 106-49-0 p-toluidine 
• 82-75-7 8-anilino-1-naphthalenesulfonate 

Relevant articles and documents

INTRAMOLECULAR DONOR-ACCEPTOR SYSTEMS. 10. MULTIPLE FLUORESCENCES FROM 8-(PHENYLAMINO)-1-NAPHTHALENESULFONATES.

8-(phenylamino)-1-naphthalenesulfonates exhibit variations in fluorescence maxima and quantum yields with solvent polarity and substituent change. These facts suggest sequential formation of two excited states, a naphthalene-excited S//1//,//n//p state and a charge-transfer state, S//1//,//c//t, as in the case of the 6-(phenylamino)-2-naphthalenesulfonates. An inefficient photochemical dissociation of the sulfonate group to form 1-(phenylamino)naphthalene is reported. Previously reported excited-state kinetics are consistent with the two-step mechanism.