129103-71-5Relevant articles and documents
Samarium(II)-mediated spirocyclization by intramolecular aryl radical addition onto an aromatic ring
Iwasaki, Hiroki,Eguchi, Toru,Tsutsui, Nozomi,Ohno, Hiroaki,Tanaka, Tetsuaki
supporting information; experimental part, p. 7145 - 7152 (2009/05/07)
(Chemical Equation Presented) Samarium(II)-mediated spirocyclization by intramolecular addition of aryl radicals onto an aromatic ring was achieved by the reaction of N-(2-iodophenyl)-N-alkylbenzamides with SmI2 in the presence of HMPA, yielding spirocyclic indolin-2-one derivatives. The ether congeners afford spirocyclic benzofuran derivatives in moderate yields by aryl radical addition onto a benzene ring without having an electron-withdrawing group. The reaction with other aryl groups such as naphthalene and indole rings is also described.