129180-75-2Relevant articles and documents
Homolysis in the Reaction of Grignard Reagents. II. The Reaction of Pyridazine
Holm, Torkil
, p. 279 - 283 (2007/10/02)
Pyridazine reacts with Grignard reagents by a homolytic mechanism as seen the presence of N-alkylated dimers, dialkyl- and trialkyl-pyrroles as well as other 'radical-type' compounds in the reaction product.The non-alkylated product 1,4-dihydropyridazine was also found.The kinetics of the reaction indicate high reactivity of tertiary and secondary reagents and low reactivity of methylmagnesium bromide as expected for a homolytic reaction.