129245-21-2

Basic information

• Product Name: (5-Aminopentyl)(phenylmethoxy)carbamic acid tert-butyl ester
• Synonyms: (5-Aminopentyl)(phenylmethoxy)carbamic acid tert-butyl ester
• CAS NO: 129245-21-2
• Molecular Formula: C₁₇H₂₈N₂O₃
• Molecular Weight: 308.419
• Mol File: 129245-21-2.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 423.605 °C at 760 mmHg
• Flash Point: 209.989 °C
• Appearance: /
• Density: 1.057
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.517
• Storage Temp.: -20°C Freezer
• Solubility: Dichloromethane, Methanol
• CAS DataBase Reference: (5-Aminopentyl)(phenylmethoxy)carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (5-Aminopentyl)(phenylmethoxy)carbamic acid tert-butyl ester(129245-21-2)
• EPA Substance Registry System: (5-Aminopentyl)(phenylmethoxy)carbamic acid tert-butyl ester(129245-21-2)

Safety Data

• Hazardous Substances Data: 129245-21-2(Hazardous Substances Data)

Usage

Uses

N-?(5-?Aminopentyl)?-?N-?(phenylmethoxy)?-?carbamic Acid 1,?1-?Dimethylethyl Ester is an intermediate in synthesizing Deferoxamine-d7 TFA Salt (D228982), a labelled Deferoxamine Mesylate (D228980), which is an iron chelating agent used in therapy for patients with sickle cell diseases and iron overload. Studies suggest that it can exert potential antioxidant neuroprotective effects in stroke patients.

InChI:InChI=1/C17H28N2O3/c1-17(2,3)22-16(20)19(13-9-5-8-12-18)21-14-15-10-6-4-7-11-15/h4,6-7,10-11H,5,8-9,12-14,18H2,1-3H3

Upstream product

• 954-81-4 N-(5-bromopentyl)phthalimide 
• 79722-21-7 tert-butyl N-(benzyloxy)carbamate 
• 111-24-0 1,5-dibromo-pentane 
• 6280-87-1 δ-chlorovaleronitrile 
• 128173-50-2 O-Benzyl-N-(tert-butoxycarbonyl)-N-(4-cyanobutyl)-hydroxylamine 

Downstream Products

• 130946-42-8 5,16,27-tris(benzyloxy)-31-cyano-4,12,15,23,26-pentaoxo-5,11,16,22,27-pentaazahentriacontanoic acid 
• 130946-43-9 5,16,27-tris(benzyloxy)-32-amino-4,12,15,23,26-pentaoxo-5,11,16,22,27-pentaazadotriacontanoic acid 
• 130946-44-0 1,12,23-tris(benzyloxy)-1,6,12,17,23,28-hexaazacyclotritriacontane-2,5,13,16,24,27-hexone 
• 26605-16-3 nocardamine 
• 112139-65-8 N'-<5-<<4-<<5-pentyl>amino>-1,4-dioxobutyl>(phenylmethoxy)amino>pentyl>-N-(4-cyanobutyl)-N-(phenylmethoxy)butanediamide 
• 130946-40-6 27--6,17-bis(benzyloxy)-7,10,18,21-tetraoxo-6,11,17,22-tetraazaheptacosanenitrile 
• 130946-41-7 27--6,17-bis(benzyloxy)-7,10,18,21-tetraoxo-6,11,17,22-tetraazaheptacosanenitrile 
• 70-51-9 deferoxamine 
• 112972-60-8 bisucaberin 
• 129245-26-7 6,17-bis(benzyloxy)-1,6,12,17-tetraazacyclodocosane-2,5,13,16-tetrone 
• 129245-25-6 21-amino-5,16-bis(benzyloxy)-4,12,15-trioxo-5,11,16-triazaheneicosanoic acid 
• 129245-23-4 N-(4-cyanobutyl)-3-<<5-<(benzyloxy)amino>pentyl>carbamoyl>-O-benzylpropionohydroxamic acid 
• 129245-24-5 5,16-bis(benzyloxy)-20-cyano-4,12,15-trioxo-5,11,16-triazaeicosanoic acid 
• 160388-25-0 1-(tert-Butoxycarbonyl)-7,18,29-tris(benzyloxy)-8,11,19,22,30-pentaoxo-1,7,12,18,23,29-hexaazahentriacontane 

Relevant articles and documents

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THE TOTAL SYNTHESIS OF BISUCABERIN

The first total synthesis of 6,17-dihydroxy-1,6,12,17-tetraazacyclodocosane-2,5,13,16-tetrone (bisucaberin) is presented.The synthetic scheme employed in this study illustrates the utility of O-benzyl-N-(tert-butoxycarbonyl)-N-(4-cyanobutyl)hydroxylamine