1295575-02-8

Basic information

• Product Name: N-(2-{3-[(ethylsulfonyl)amino]phenoxy}-4-fluoro-6-[(2-fluoro-4-iodophenyl)amino]phenyl)-2-hydroxyethanesulfonamide
• Synonyms: N-(2-{3-[(ethylsulfonyl)amino]phenoxy}-4-fluoro-6-[(2-fluoro-4-iodophenyl)amino]phenyl)-2-hydroxyethanesulfonamide
• CAS NO: 1295575-02-8
• Molecular Weight: 653.466
• Mol File: 1295575-02-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(2-{3-[(ethylsulfonyl)amino]phenoxy}-4-fluoro-6-[(2-fluoro-4-iodophenyl)amino]phenyl)-2-hydroxyethanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-{3-[(ethylsulfonyl)amino]phenoxy}-4-fluoro-6-[(2-fluoro-4-iodophenyl)amino]phenyl)-2-hydroxyethanesulfonamide(1295575-02-8)
• EPA Substance Registry System: N-(2-{3-[(ethylsulfonyl)amino]phenoxy}-4-fluoro-6-[(2-fluoro-4-iodophenyl)amino]phenyl)-2-hydroxyethanesulfonamide(1295575-02-8)

Safety Data

• Hazardous Substances Data: 1295575-02-8(Hazardous Substances Data)

Upstream product

• 1295567-66-6 N-(3-{5-fluoro-3-[(2-fluoro-4-iodophenyl)amino]-2-nitrophenoxy}phenyl)ethanesulfonamide 
• 1295567-65-5 3-(3-aminophenoxy)-5-fluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline 
• 765962-75-2 3,5-difluoro-N-(2-fluoro-4-iodophenyl)-2-nitroaniline 
• 29632-74-4 2-fluro-4-iodoaniline 
• 315-14-0 1,3,5-trifluoro-2-nitrobenzene 
• 1295567-67-7 N-(3-{2-amino-5-fluoro-3-[(2-fluoro-4-iodophenyl)amino]phenoxy}phenyl)ethanesulfonamide 
• 78303-70-5 2-hydroxyethane-1-sulfonyl chloride 
• 1295574-98-9 methyl [(2-{3-[(ethylsulfonyl)amino]phenoxy}-4-fluoro-6-[(2-fluoro-4-iodophenyl)amino]phenyl)-sulfamoyl]acetate 

Relevant articles and documents

Modular Assembly of Allosteric MEK Inhibitor Structural Elements Unravels Potency and Feedback-Modulation Handles

Having recently identified a so-far unexplored area adjacent to the known binding site of allosteric mitogen-activated protein kinase kinase (MEK) inhibitors, we now report an extension of these studies by combining our new side chains with different MEK