129644-61-7

Basic information

• Product Name: Benzene, 1,2-bis(trifluoromethoxy)-
• CAS NO: 129644-61-7
• Molecular Formula: C8H4F6O2
• Molecular Weight: 246.109
• Mol File: 129644-61-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzene, 1,2-bis(trifluoromethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,2-bis(trifluoromethoxy)-(129644-61-7)
• EPA Substance Registry System: Benzene, 1,2-bis(trifluoromethoxy)-(129644-61-7)

Safety Data

• Hazardous Substances Data: 129644-61-7(Hazardous Substances Data)

Upstream product

• 56-23-5 tetrachloromethane 
• 32858-93-8 2-(trifluoromethoxy)phenol 
• 129644-60-6 1,2-bistrichloromethoxybenzene 

Downstream Products

• 603-45-2 aurin 

Relevant articles and documents

Lability of the trifluoromethyl group of trifluoromethoxybenzenes under HF/Lewis acid conditions

The trifluoromethyl functionality of trifluoromethoxybenzenes (trifluoromethyl phenyl ethers) becomes labile under HF/Lewis acid conditions. Substrates with an unsubstituted para-position shed their -CF3 groups while performing a Friedel-Crafts reaction upon another substrate molecule's trifluoromethoxy group to generate p-rosolic acids. Substrates that had blocking groups at the para-positions reacted ortho. The electron donating substituents methoxy and phenoxy interfered with the formation of rosolic acids.