129687-65-6

Basic information

• Product Name: 2-(m-nitrophenyl)-4,4-bis(hydroxymethyl)oxazolidine
• Synonyms: 2-(m-nitrophenyl)-4,4-bis(hydroxymethyl)oxazolidine
• CAS NO: 129687-65-6
• Molecular Weight: 254.243
• Mol File: 129687-65-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(m-nitrophenyl)-4,4-bis(hydroxymethyl)oxazolidine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(m-nitrophenyl)-4,4-bis(hydroxymethyl)oxazolidine(129687-65-6)
• EPA Substance Registry System: 2-(m-nitrophenyl)-4,4-bis(hydroxymethyl)oxazolidine(129687-65-6)

Safety Data

• Hazardous Substances Data: 129687-65-6(Hazardous Substances Data)

Upstream product

• 99-61-6 3-nitro-benzaldehyde 
• 77-86-1 2-amino-2-hydroxymethyl-1,3-propanediol 

Downstream Products

• 1252783-75-7 1,3-diacetoxy-2-acetoxymethyl-2-(3-nitrobenzylideneamino)propane 

Relevant articles and documents

An anomeric effect drives the regiospecific ring-opening of 1,3-oxazolidines under acetylating conditions

A series of oxazolidines derived from tris(hydroxymethyl)-aminomethane (TRIS; 1), have been prepared efficiently. Geometries optimized at the B3LYP/6-31G* level of theory, along with the crystal data of compounds 9 and 12 and NOESY correlations

Genotoxicity in oxazolidine derivatives: influence of the nitro group

Tris-(hydroxymethyl)-aminomethane reacts with various aromatic or heterocyclic aldehydes, leading to new mono- or bicyclic oxazolidine derivatives.The importance of molecular surroundings of the nitro group has been evaluated by the genotoxic study of syn