129721-53-5Relevant articles and documents
Dioxygen-promoted Pd-catalyzed aminocarbonylation of organoboronic acids with amines and CO: A direct approach to tertiary amides
Ren, Long,Li, Xinwei,Jiao, Ning
supporting information, p. 5852 - 5855 (2016/11/29)
A direct approach from organoboronic acids and amines to tertiary amides via Pd-catalyzed aerobic aminocarbonylation has been developed. The presence of O2 significantly promotes the efficiency of this transformation. This method uses commercially available organoboronic acids and cheap CO and O2 (1 atm), which renders amides an easy synthesis with broad substrate scope and high functional group tolerance.
Conformational arm-wrestling: Battles for stereochemical control in benzamides bearing matched and mismatched chiral 2- and 6-substituents
Clayden, Jonathan,Foricher, Yann J. Y.,Helliwell, Madeleine,Johnson, Paul,Mitjans, David,Vinader, Victoria
, p. 444 - 454 (2008/01/27)
The orientation of a tertiary amide group adjacent to an aromatic ring may be governed by the stereochemistry of an adjacent chiral substituent. With a chiral substituent in both ortho positions, matched/mismatched pairs of isomers result. Evidence for ma