1297309-38-6

Basic information

• Product Name: 3-phenylacetyl-2-(2RS,4R)-furan-2-yl-thiazolidine-4-carboxylic acid
• Synonyms: 3-phenylacetyl-2-(2RS,4R)-furan-2-yl-thiazolidine-4-carboxylic acid
• CAS NO: 1297309-38-6
• Molecular Weight: 317.365
• Mol File: 1297309-38-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-phenylacetyl-2-(2RS,4R)-furan-2-yl-thiazolidine-4-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-phenylacetyl-2-(2RS,4R)-furan-2-yl-thiazolidine-4-carboxylic acid(1297309-38-6)
• EPA Substance Registry System: 3-phenylacetyl-2-(2RS,4R)-furan-2-yl-thiazolidine-4-carboxylic acid(1297309-38-6)

Safety Data

• Hazardous Substances Data: 1297309-38-6(Hazardous Substances Data)

Upstream product

• 72678-98-9 (2RS,4R)-2-(furan-2-yl)thiazolidine-4-carboxylic acid 
• 103-80-0 phenylacetyl chloride 
• 98-01-1 furfural 

Relevant articles and documents

Design, synthesis and biological activity of thiazolidine-4-carboxylic acid derivatives as novel influenza neuraminidase inhibitors

A series of thiazolidine-4-carboxylic acid derivatives were synthesized and evaluated for their ability to inhibit neuraminidase (NA) of influenza A virus. All the compounds were synthesized in good yields starting from commercially available l-cysteine hydrochloride using a suitable synthetic strategy. These compounds showed moderate inhibitory activity against influenza A neuraminidase. The most potent compound of this series is compound 4f (IC50 = 0.14 μM), which is about sevenfold less potent than oseltamivir and could be used to design novel influenza NA inhibitors that exhibit increased activity based on thiazolidine ring.