129748-56-7

Basic information

• Product Name: N-(2-bromoethyl)-N-(2-propenyl)-4-methylbenzenesulfonamide
• Synonyms: N-(2-bromoethyl)-N-(2-propenyl)-4-methylbenzenesulfonamide
• CAS NO: 129748-56-7
• Molecular Weight: 318.235
• Mol File: 129748-56-7.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: N-(2-bromoethyl)-N-(2-propenyl)-4-methylbenzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-bromoethyl)-N-(2-propenyl)-4-methylbenzenesulfonamide(129748-56-7)
• EPA Substance Registry System: N-(2-bromoethyl)-N-(2-propenyl)-4-methylbenzenesulfonamide(129748-56-7)

Safety Data

• Hazardous Substances Data: 129748-56-7(Hazardous Substances Data)

Upstream product

• 50487-71-3 4-methyl-N-(2-propenyl)benzenesulfonamide 
• 98-59-9 p-toluenesulfonyl chloride 
• 70-55-3 toluene-4-sulfonamide 
• 10017-11-5 allylammonium chloride 
• 106-93-4 ethylene dibromide 
• 869275-28-5 N-allyl-N-(ethoxycarbonylmethyl)toluene-4-sulfonamide 
• 869275-29-6 N-allyl-N-(2-hydroxyethyl)-4-methylbenzenesulfonamide 

Downstream Products

• 863418-78-4 N-allyl-N-ethyl-4-methyl-benzenesulfonamide 
• 86553-37-9 3-methyl-1-tosylpyrrolidine 
• 50487-71-3 4-methyl-N-(2-propenyl)benzenesulfonamide 

Relevant articles and documents

Halogenation of primary alcohols using a tetraethylammonium halide/[Et 2NSF2]BF4 combination

The halogenation of primary alcohols is presented. The use of a combination of tetraethylammonium halide and [Et2NSF2]BF4 (XtalFluor-E) allows for chlorination and bromination reactions to proceed efficiently (up to 92% yield) with a wide range of alcohols. Iodination reactions are also possible albeit in lower yields.

Formal Bromine Atom Transfer Radical Addition of Nonactivated Bromoalkanes Using Photoredox Gold Catalysis

Organic transformations mediated by photoredox catalysis have been at the forefront of reaction discovery. Recently, it has been demonstrated that binuclear Au(I) bisphosphine complexes, such as [Au2(μ-dppm)2]X2, are capable of mediating electron transfer to nonactivated bromoalkanes for the generation of a variety of alkyl radicals. The transfer reactions of bromine, derived from nonactivated bromoalkanes, are largely unknown. Therefore, we propose that unique metal-based mechanistic pathways are at play, as this binuclear gold catalyst has been known to produce Au(III) Lewis acid intermediates. The scope and proposed mechanistic overview for the formal bromine atom transfer reaction of nonactivated bromoalkanes mediated by photoredox Au(I) catalysis is presented. The methodology presented afforded good yields and a broad scope which include examples using bromoalkanes and iodoarenes.

Copper(I)-Catalyzed Stereo- and Chemoselective Borylative Radical Cyclization of Alkyl Halides Bearing an Alkene Moiety

The stereoselective borylative radical cyclization of alkyl halides containing an alkene moiety was developed using a copper(I)/diboron catalyst system. The optimized reaction conditions allowed us to control the chemoselectivity between the allylic substitution and the borylative radical cyclization. The borylation products were subsequently converted to highly functionalized organic compounds by derivatization of the newly formed C-B bond. This borylative radical cyclization offers a novel methodology for the stereoselective synthesis of various heterocyclic compounds.