129780-84-3

Basic information

• Product Name: di-tert-butyl N-<4-<<(4-amino-2-methylpteridin-6-yl)methyl>methylamino>benzoyl>-L-glutamate
• CAS NO: 129780-84-3
• Molecular Weight: 565.673
• Mol File: 129780-84-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: di-tert-butyl N-<4-<<(4-amino-2-methylpteridin-6-yl)methyl>methylamino>benzoyl>-L-glutamate(CAS DataBase Reference)
• NIST Chemistry Reference: di-tert-butyl N-<4-<<(4-amino-2-methylpteridin-6-yl)methyl>methylamino>benzoyl>-L-glutamate(129780-84-3)
• EPA Substance Registry System: di-tert-butyl N-<4-<<(4-amino-2-methylpteridin-6-yl)methyl>methylamino>benzoyl>-L-glutamate(129780-84-3)

Safety Data

• Hazardous Substances Data: 129780-84-3(Hazardous Substances Data)

Upstream product

• 40127-91-1 2-Amino-5-chloromethylpyrazine-3-carbonitrile 
• 10541-83-0 N-methyl-p-aminobenzoic acid 
• 32677-01-3 L-glutamic acid di-tert-butyl ester hydrochloride 
• 129780-83-2 4-<<(4-amino-2-methylpteridin-6-yl)methyl>methylamino>benzoic acid 

Relevant articles and documents

Synthesis and biological activity of the 2-desamino and 2-desamino-2-methyl analogues of aminopterin and methotrexate

The previously undescribed 2-desamino and 2-desamino-2-methyl analogues of aminopterin (AMT) and methotrexate (MTX) were synthesized from 2-amino-5-(chloromethyl)pyrazine-3- carbonitrile. The AMT analogues were obtained via a three-step sequence consistin