129993-47-1 Usage
General Description
1-Methyl-1H-imidazole-4-carboxamide, also known as 4-carbamoyl-1-methylimidazole, is a chemical compound with the molecular formula C5H6N2O. It is a derivative of imidazole and is commonly used in the synthesis of pharmaceuticals and as a building block in organic chemistry. 1-Methyl-1H-imidazole-4-carboxamide is a white, odorless powder with a melting point of 203-206°C and is soluble in water, methanol, and ethanol. It has various biological activities, including anti-bacterial, anti-fungal, and anti-tumor properties, making it a valuable precursor in drug-development research. Additionally, 1-Methyl-1H-imidazole-4-carboxamide has been implicated in the regulation of gene expression and as a potential therapeutic agent for cardiovascular and neurological conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 129993-47-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,9,9,9 and 3 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 129993-47:
(8*1)+(7*2)+(6*9)+(5*9)+(4*9)+(3*3)+(2*4)+(1*7)=181
181 % 10 = 1
So 129993-47-1 is a valid CAS Registry Number.
InChI:InChI=1/C5H7N3O/c1-8-2-4(5(6)9)7-3-8/h2-3H,1H3,(H2,6,9)
129993-47-1Relevant articles and documents
HETEROARYL ALKYLENE SUBSTITUTED 2-OXOQUINAZOLINE DERIVATIVES AS INHIBITORS OF METHIONINE ADENOSYLTRANSFERASE 2A
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Paragraph 0366, (2021/12/31)
Disclosed herein are certain heteroaryl alkylene substituted 2-oxoquinazoline derivatives of Formula (I): (I) that are methionine adenosyltransferase 2A (MAT2A) inhibitors. Also disclosed are pharmaceutical compositions comprising such compounds and methods of treating diseases treatable by inhibition of MAT2A such as cancer, including cancers characterized by reduced or absence of methylthioadenosine phosphorylase (MTAP) activity.
Thiazole benzamide derivatives and pharmaceutical compositions for inhibiting cell proliferation, and methods for their use
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Page 37-38, (2010/02/03)
Aminothiazole compounds with mono-/di-substituted benzamide are represented by the Formula (I), and their pharmaceutically acceptable salts, pharmaceutically acceptable prodrugs, pharmaceutically active metabolites, and pharmaceutically acceptable salts of said metabolites are described. These agents modulate and/or inhibit the cell proliferation and activity of protein kinases and are useful as pharmaceuticals for treating malignancies and other disorders.
