130-24-5

Basic information

• Product Name: VITAMIN K5
• Synonyms: 2-Methyl-4-amino-1-hydroxynaphthalenehydrochloride;VitaminK5HCl;4-AMino-2-Methyl-1-naphthalenol Hydrochloride;4-Amino-2-methylnaphthol hydrochloride;Synkamin hydrochloride;4-AMINO-2-METHYL-1-NAPHTHOL HYDROCHLORIDE;2-METHYL-4-AMINO-1-NAPHTHOL HCL;2-METHYL-4-AMINO-1-NAPHTHOL HYDROCHLORIDE
• CAS NO: 130-24-5
• Molecular Formula: C11H12ClNO
• Molecular Weight: 209.67
• EINECS: 204-983-9
• Mol File: 130-24-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 280 °C (decomp)
• Boiling Point: 385.1oC at 760 mmHg
• Flash Point: 186.7oC
• Appearance: /
• Vapor Pressure: 1.75E-06mmHg at 25°C
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• CAS DataBase Reference: VITAMIN K5(CAS DataBase Reference)
• NIST Chemistry Reference: VITAMIN K5(130-24-5)
• EPA Substance Registry System: VITAMIN K5(130-24-5)

Safety Data

• Hazardous Substances Data: 130-24-5(Hazardous Substances Data)

Usage

Uses

Chemical probe to study insulin-activated hexose transport.

Purification Methods

Crystallise it from dilute HCl. [Sah Recl Trav Chim Pays-Bas 59 458 1941, Sah Recl Trav Chim Pays-Bas 60 373 1940, Veldstra & Wiardi Recl Trav Chim Pays-Bas 61 547 1942, Veldstra & Wiardi Recl Trav Chim Pays-Bas 62 75 1943, Beilstein 13 III 1921.]

InChI:InChI=1/C11H11NO.ClH/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13;/h2-6,13H,12H2,1H3;1H

Synthetic route

4-amino-2-methyl-[1]naphthol; hydrochloride (130-24-5) + potassium-hexacyanoferrate(III) → menadione (58-27-5)

Conditions	Yield
vom pH 6;

4-amino-2-methyl-[1]naphthol; hydrochloride (130-24-5) + air → 2-methyl-[1,4]naphthoquinone-4-(4-hydroxy-3-methyl-[1]naphthylimine) (70150-76-4)

Conditions	Yield
vom pH 4-5;

4-amino-2-methyl-[1]naphthol; hydrochloride (130-24-5) + potassium hexacyanoferrate(III) → 2-methyl-[1,4]naphthoquinone-4-(4-hydroxy-3-methyl-[1]naphthylimine) (70150-76-4)

Conditions	Yield
vom pH 4-5;