13009-99-9 Usage
Description
Mafenide acetate, also known as 4-(Aminomethyl)benzenesulfonamide acetate or Sulfamylon, is a homologue of the sulfanilamide molecule. It is a crystalline solid that is not a true sulfanilamide-type compound, as it is not inhibited by PABA. Mafenide acetate possesses unique antibacterial properties and is particularly effective against Clostridium welchii in topical applications.
Uses
Used in Pharmaceutical Industry:
Mafenide acetate is used as an antibacterial agent for the treatment of slow-healing, infected wounds. Its mechanism of action differs from that of true sulfanilamide-type compounds, making it a valuable addition to the arsenal of antibiotics. It is often used in combination with other antibiotics to enhance the treatment of wounds.
Used in Military Applications:
During World War II, the German army utilized Mafenide acetate for prophylaxis of wounds, recognizing its effectiveness in preventing infection and promoting healing.
Used in Burn Treatment:
Mafenide acetate is also used in the treatment of burns, particularly in cases where large quantities of the drug are required. However, some patients have developed metabolic acidosis as a result of its use, leading to the development of new organic salts to mitigate this adverse effect. The acetate in an ointment base has proven to be the most efficacious form for this application.
Therapeutic Function
Antibacterial
Check Digit Verification of cas no
The CAS Registry Mumber 13009-99-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,0,0 and 9 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 13009-99:
(7*1)+(6*3)+(5*0)+(4*0)+(3*9)+(2*9)+(1*9)=79
79 % 10 = 9
So 13009-99-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H10N2O2S.C2H4O2/c8-5-6-1-3-7(4-2-6)12(9,10)11;1-2(3)4/h1-4H,5,8H2,(H2,9,10,11);1H3,(H,3,4)
