130188-81-7

Basic information

• Product Name: 2-([1,1′-biphenyl]-4-ylsulfonyl)-1-phenylethan-1-one
• Synonyms: 2-([1,1′-biphenyl]-4-ylsulfonyl)-1-phenylethan-1-one
• CAS NO: 130188-81-7
• Molecular Weight: 336.411
• Mol File: 130188-81-7.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 2-([1,1′-biphenyl]-4-ylsulfonyl)-1-phenylethan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-([1,1′-biphenyl]-4-ylsulfonyl)-1-phenylethan-1-one(130188-81-7)
• EPA Substance Registry System: 2-([1,1′-biphenyl]-4-ylsulfonyl)-1-phenylethan-1-one(130188-81-7)

Safety Data

• Hazardous Substances Data: 130188-81-7(Hazardous Substances Data)

Upstream product

• 5122-94-1 4-biphenylboronic acid 
• 70-11-1 α-bromoacetophenone 
• 536-74-3 phenylacetylene 
• 2206-94-2 1-acetoxy-1-phenylethene 
• 1623-93-4 4-diphenylsulfonyl chloride 
• 13735-81-4 1-styrenyloxytrimethylsilane 
• 1591-31-7 4-iodo-biphenyl 
• 492-38-6 2-phenylacrylic acid 
• 855276-86-7 4-biphenylsulfonyl hydrazide 

Relevant articles and documents

Photo-Mediated Decarboxylative Ketonization of Atropic Acids with Sulfonyl Hydrazides: Direct Access to β-Ketosulfones

An efficient formation of synthetically and biologically relevant β-ketosulfones via a photo-mediated decarboxylative ketonization of atropic acids was disclosed. The approach features metal-free conditions, good functional group compatibility, readily available starting materials and the use of ubiquitous dioxygen as both oxygen source and oxidant. Furthermore, mechanistic studies reveal that the decarboxylative ketonization reaction proceeds via a radical mechanism and may involve a radical chain reaction. (Figure presented.).

Method for preparing β-ketone sulfone compound through visible light-mediated atorvastatin decarboxylation reaction (by machine translation)

The preparation method of the invention has the characteristics β - that raw materials are simple and easy to obtain, the operation is simple . the reaction conditions are mild, and the reaction system is not sensitive to water . is a method for preparing,ketone sulfone compounds, by using environment-friendly (-source extensive atorvastatin as reactants), and then fully dissolving β -communicating oxygen balloon, in a mixed solvent of acetonitrile and water to obtain, ketal sulphone compounds by reacting, with a stable odorless sulfonyl hydrazide in a mixed solvent of acetonitrile and water under the irradiation of visible light. (by machine translation)

Synthesis of β-Keto Sulfones via Coupling of Aryl/Alkyl Halides, Sulfur Dioxide and Silyl Enolates through Metal-Free Photoinduced C–X Bond Dissociation

A photoinduced sulfonylative coupling of aryl/alkyl halides, DABCO?(SO2)2 (1,4-diazabicyclo[2.2.2]octane-sulfur dioxide), and silyl enolates under metal-free conditions has been developed, giving rise to β-keto sulfones in good yields. This transformation proceeds smoothly at room temperature under ultraviolet irradiation with good tolerance of various functional groups. Aryl iodides/bromides and alkyl halides are all good substrates in the sulfonylative reaction. A plausible mechanism is proposed, which proceeds through a radical process under photoinduced conditions. (Figure presented.).